高分子材料与工程
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徐翔 博士
日期:2025-03-27 作者: 编辑: 点击数:

一、基本情况

徐翔19949月,安徽安庆人,中共党员,博士。

二、教育与工作经历

2013.09-2017.07,安徽建筑大学,高分子材料与工程专业,本科

2017.09-2020.07桂林理工大学高分子化学与物理,硕士

2020.09-2024.06大连理工大学高分子材料,博士

2024.06-至今,桂林理工大学材料科学与工程学院,师资博士后/教师

  1. 科学研究

三、研究方向:

  1. 生物高分子材料的可控制备与应用,如基于NCA的开环聚合制备功能性聚氨基酸,并用于肿瘤治疗和基因/药物递送等领域。

  2. 生物基高分子材料的制备与应用

  3. 多功能自修复材料的制备与应用

    已在Chemical ScienceSmallScience China ChemistryGreen Synthesis and CatalysisMacromoleculeBiomacromoleculePolymer ChemistryComposites Communications等国际学术期刊上正式发表SCI论文16,其中,第一/通讯作者论文12篇。

     

     主持/参与科研项目:

  4. 广西自然科学基金项目,2018GXNSFBA281121,催化配位挤出共聚制备原位聚乙烯复合材料,2019.01-2021.1210万元,结题,参与;

  5. 国家自然科学基金地区项目,51863007,松香基聚氨酯微球构建及功能化研究,2019.01-2022.1240万,结题,参与。

  6. 桂林理工大学引进人才科研启动项目GUTQDJJ 20240292024-06至今在研主持。

    代表性科研成果(近五年的论文和专利):

[1] Xu X, Ma J J, Wang A G, Zheng N*. N-sulfonyl amidine polypeptides: new polymeric biomaterials with conformation transition responsive to tumor acidity. Chemical Science 2024, 15(5): 1769-1781.

[2] Xu X, Ma J J, Zheng Y B, Wang S L, Wang A G*, Zheng N*. Secondary structure in overcoming photosensitizers' aggregation: α-helical polypeptides for enhanced photodynamic therapy. Advanced Healthcare Materials 2023, 12(21): 2203386.

[3] Xu X, Liang R M, Zheng Y B, Qiu Y, Zheng N*. Sulfated glycomimetic α-helical polypeptides for antiviral activity. Biomacromolecules 2023, 24(7): 3115-3126.

[4] Xu X, Liu S X, Gao H, Li M, He J N, Zheng Y B, Song W Z, Zheng N*. Versatile fully-substituted triazole-functionalized polypeptides with a stable α-helical conformation for gene delivery. Polymer Chemistry 2022, 13(35): 5042-5047.

[5] Bai J P, Xu X (co-first author), Zheng Y B, Song W Z*, Zheng N*. Metal-free and water-compatible nanocatalysts for green photocatalytic dehydrogenation in aqueous medium. Green Synthesis and Catalysis 2024, 5(3):186-190.

[6] Xu X, He J J, Zeng Y N, Yu C L, Zhang F A*. Controllable surface-initiated metal-free atom transfer radical polymerization of methyl methacrylate on mesoporous SBA-15 via reductive quenching. European Polymer Journal 2020, 131: 109724.

[7] Xing Y D, Li J C, Cheng J, Lu L W, Xue T, Xu J B, Xu X*, Zhang F A*. 2D polyamides enable self-healing and recyclable elastomers with high robustness, toughness, and crack resistance via supramolecular interactions. Small 2025, 21(5): 2411040.

[8] Li J C, Xing Y D, Liu H M, Lu L W, Xue T, Xu X*, Zhang F A*. Fabrication of thermally activated fire-extinguishing microcapsules and silicone rubber composite. Composites Communications 2025, 53: 102256.

[9] Xu J B, Xing Y D, Cheng J, Niu W Z, Shi Z Y, Xu X M, Xu X*, Zhang F A*. Engineered functional segments enabled mechanically robust, photothermal self-healing, recyclable, and durable rosin-based superhydrophobic composite coatings. Composites Communications 2025, 56: 102345.

[10] Xu X, Zeng Y N, Yu C L*, Zhang F A*. Controlled RAFT polymerization of MMA in confined space of various pore sizes of SBA-15. Journal of Porous Materials 2020, 27(1): 95-105.[11] Xu X, Zou Y, He J J, Zeng Y N, Yu C L*, Zhang F A*. Insight into the effects of reaction conditions on metal-free surface-initiated atom-transfer radical polymerization of methyl methacrylate from SBA-15. Journal of Applied Physics 2020, 127(11): 115102.[12] Xu X M, Xu X, Zeng Y N, Zhang F A*. Oxygen-tolerant photo-induced metal-free atom transfer radical polymerization. Journal of Photochemistry and Photobiology A-Chemistry 2021, 411: 113191.

[13] Liu S X, Ma J J, Xu X, Wang A G, Zheng N*. Ultrasound-driven self-decomposition porphyrins as metal-free CO precursors for gas and sonodynamic synergistic therapy. Science China Chemistry 2024, 67(5): 1624-1635.

[14] Liu Y, Zhou L Y, Xu X, Cheng Z H, Chen Y J, Mei X A, Zheng N*, Zhang C H*, Bai Y G*. Combination of backbone rigidity and richness in aryl structures enables direct membrane translocation of polymer scaffolds for efficient gene delivery. Biomacromolecules 2023, 24(12): 5698-5706.

[16] Li M, Duan X L, Jiang Y, Sun X H, Xu X, Zheng Y B, Song W Z*, Zheng N*. Multicomponent polymerization of azides, alkynes, and electrophiles toward 1,4,5-trisubstituted polytriazoles . Macromolecules 2022, 55(16): 7240-7248.

 (二)申请和授权专利

  1. 郑楠, 宋汪泽, 徐翔. 一种水溶性聚多肽光敏剂、制备方法及光动力治疗应用: 中国. 发明类别: 发明专利. 授权公告号: CN 116444788 B [P], 授权日期: 2024.04.17.

  2. 郑楠, 宋汪泽, 徐翔.一种硫酸化糖多肽、制备方法及抗病毒应用: 中国. 发明类别: 发明专利. 授权公告号: CN 116655906 B [P], 授权日期: 2024.03.29.

四、联系方式

    通信地址:广西桂林市建干路12号桂林理工大学材料科学与工程学院(541004
        E-mailxuxiang@glut.edu.cn

 

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